Restored insulin-sensitivity in IRS-1–deficient mice treated by adenovirus-mediated gene therapy

Insulin resistance is commonly observed both in overt diabetes and in individuals prone to, but not yet manifesting, diabetes. Hence the maintenance or restoration of insulin sensitivity may prevent the onset of this disease. We previously showed that homozygous disruption of insulin receptor substr...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Ueki, Kohjiro, Yamauchi, Toshimasa, Tamemoto, Hiroyuki, Tobe, Kazuyuki, Yamamoto-Honda, Ritsuko, Kaburagi, Yasushi, Akanuma, Yasuo, Yazaki, Yoshio, Aizawa, Sininchi, Nagai, Ryozo, Kadowaki, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2000
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Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC315460/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10811851/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI7656
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