Adrenalectomy reduces neuropeptide Y–induced insulin release and NPY receptor expression in the rat ventromedial hypothalamus

Chronic central administration of neuropeptide Y (NPY) causes hyperphagia, hyperinsulinemia, and obesity, a response that is prevented by prior adrenalectomy (ADX) in rats. The basis of NPY’s effect and how the acute responses to this peptide are affected by ADX remain unknown. This study investigat...

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Detalles Bibliográficos

Publicado en:	J Clin Invest
Autores principales:	Wisialowski, Todd, Parker, Rachel, Preston, Elaine, Sainsbury, Amanda, Kraegen, Edward, Herzog, Herbert, Cooney, Gregory
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Clinical Investigation 2000
Materias:	Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC315443/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10792000/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI8695
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