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Adrenalectomy reduces neuropeptide Y–induced insulin release and NPY receptor expression in the rat ventromedial hypothalamus

Chronic central administration of neuropeptide Y (NPY) causes hyperphagia, hyperinsulinemia, and obesity, a response that is prevented by prior adrenalectomy (ADX) in rats. The basis of NPY’s effect and how the acute responses to this peptide are affected by ADX remain unknown. This study investigat...

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書誌詳細
出版年:J Clin Invest
主要な著者: Wisialowski, Todd, Parker, Rachel, Preston, Elaine, Sainsbury, Amanda, Kraegen, Edward, Herzog, Herbert, Cooney, Gregory
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC315443/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10792000/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI8695
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