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Adrenalectomy reduces neuropeptide Y–induced insulin release and NPY receptor expression in the rat ventromedial hypothalamus

Chronic central administration of neuropeptide Y (NPY) causes hyperphagia, hyperinsulinemia, and obesity, a response that is prevented by prior adrenalectomy (ADX) in rats. The basis of NPY’s effect and how the acute responses to this peptide are affected by ADX remain unknown. This study investigat...

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Bibliografski detalji
Izdano u:J Clin Invest
Glavni autori: Wisialowski, Todd, Parker, Rachel, Preston, Elaine, Sainsbury, Amanda, Kraegen, Edward, Herzog, Herbert, Cooney, Gregory
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2000
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC315443/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10792000/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI8695
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