Adrenalectomy reduces neuropeptide Y–induced insulin release and NPY receptor expression in the rat ventromedial hypothalamus

Chronic central administration of neuropeptide Y (NPY) causes hyperphagia, hyperinsulinemia, and obesity, a response that is prevented by prior adrenalectomy (ADX) in rats. The basis of NPY’s effect and how the acute responses to this peptide are affected by ADX remain unknown. This study investigat...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Wisialowski, Todd, Parker, Rachel, Preston, Elaine, Sainsbury, Amanda, Kraegen, Edward, Herzog, Herbert, Cooney, Gregory
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 2000
Schlagworte:	Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC315443/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10792000/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI8695
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