Adrenalectomy reduces neuropeptide Y–induced insulin release and NPY receptor expression in the rat ventromedial hypothalamus

Chronic central administration of neuropeptide Y (NPY) causes hyperphagia, hyperinsulinemia, and obesity, a response that is prevented by prior adrenalectomy (ADX) in rats. The basis of NPY’s effect and how the acute responses to this peptide are affected by ADX remain unknown. This study investigat...

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Pubblicato in:	J Clin Invest
Autori principali:	Wisialowski, Todd, Parker, Rachel, Preston, Elaine, Sainsbury, Amanda, Kraegen, Edward, Herzog, Herbert, Cooney, Gregory
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 2000
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC315443/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10792000/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI8695
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