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Maximum Likelihood Genome Assembly

Whole genome shotgun assembly is the process of taking many short sequenced segments (reads) and reconstructing the genome from which they originated. We demonstrate how the technique of bidirected network flow can be used to explicitly model the double-stranded nature of DNA for genome assembly. By...

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Bibliografske podrobnosti
Main Authors: Medvedev, Paul, Brudno, Michael
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154397/
https://ncbi.nlm.nih.gov/pubmed/19645596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2009.0047
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