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Maximum Likelihood Genome Assembly

Whole genome shotgun assembly is the process of taking many short sequenced segments (reads) and reconstructing the genome from which they originated. We demonstrate how the technique of bidirected network flow can be used to explicitly model the double-stranded nature of DNA for genome assembly. By...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Medvedev, Paul, Brudno, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154397/
https://ncbi.nlm.nih.gov/pubmed/19645596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2009.0047
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