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Maximum Likelihood Genome Assembly

Whole genome shotgun assembly is the process of taking many short sequenced segments (reads) and reconstructing the genome from which they originated. We demonstrate how the technique of bidirected network flow can be used to explicitly model the double-stranded nature of DNA for genome assembly. By...

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Detalhes bibliográficos
Main Authors: Medvedev, Paul, Brudno, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154397/
https://ncbi.nlm.nih.gov/pubmed/19645596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2009.0047
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