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Cellular studies reveal mechanistic differences between taccalonolide A and paclitaxel
Taccalonolide A is a microtubule stabilizer that has cellular effects almost identical to paclitaxel. However, biochemical studies show that, unlike paclitaxel, taccalonolide A does not enhance purified tubulin polymerization or bind tubulin/microtubules. Mechanistic studies aimed at understanding t...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3154365/ https://ncbi.nlm.nih.gov/pubmed/21597323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.13.16238 |
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