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The taccalonolides and paclitaxel cause distinct effects on microtubule dynamics and aster formation
BACKGROUND: Microtubule stabilizers suppress microtubule dynamics and, at the lowest antiproliferative concentrations, disrupt the function of mitotic spindles, leading to mitotic arrest and apoptosis. At slightly higher concentrations, these agents cause the formation of multiple mitotic asters wit...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4015978/ https://ncbi.nlm.nih.gov/pubmed/24576146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-41 |
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