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The taccalonolides, novel microtubule stabilizers, and γ-radiation have additive effects on cellular viability
The taccalonolides are novel antimitotic microtubule stabilizers that have a unique mechanism of action independent of a direct interaction with tubulin. Cytotoxicity and clonogenic assays show that taccalonolide A and radiation act in an additive manner to cause cell death. The taxanes and epothilo...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3104079/ https://ncbi.nlm.nih.gov/pubmed/21507571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2011.03.022 |
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