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The taccalonolides, novel microtubule stabilizers, and γ-radiation have additive effects on cellular viability

The taccalonolides are novel antimitotic microtubule stabilizers that have a unique mechanism of action independent of a direct interaction with tubulin. Cytotoxicity and clonogenic assays show that taccalonolide A and radiation act in an additive manner to cause cell death. The taxanes and epothilo...

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Sonraí Bibleagrafaíochta
Main Authors: Risinger, April L., Natarajan, Mohan, Thomas, Charles R., Mooberry, Susan L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104079/
https://ncbi.nlm.nih.gov/pubmed/21507571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2011.03.022
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