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Identification and Biological Activities of New Taccalonolide Microtubule Stabilizers

The taccalonolides are a unique class of microtubule stabilizers that do not bind directly to tubulin. Three new taccalonolides, Z, AA and AB, along with two known compounds, taccalonolides R and T, were isolated from Tacca chantrieri and Tacca integrifolia. Taccalonolide structures were determined...

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Main Authors: Peng, Jiangnan, Risinger, April L., Fest, Gary A., Jackson, Evelyn M., Helms, Gregory, Polin, Lisa A., Mooberry, Susan L.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180930/
https://ncbi.nlm.nih.gov/pubmed/21800839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm200757g
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