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Hydrolysis Reactions of the Taccalonolides Reveal Structure Activity Relationships
The taccalonolides are microtubule stabilizers isolated from plants of the genus Tacca that show potent in vivo antitumor activity and the ability to overcome multiple mechanisms of drug resistance. The most potent taccalonolide identified to date, AJ, is a semisynthetic product generated from the m...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3761391/ https://ncbi.nlm.nih.gov/pubmed/23855953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np400435t |
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