Cross-bridge Kinetics in Myofibrils Containing Familial Hypertrophic Cardiomyopathy R58Q Mutation in the Regulatory Light Chain of Myosin

Familial hypertrophic cardiomyopathy (FHC) is a heritable form of cardiac hypertrophy caused by single-point mutations in genes encoding sarcomeric proteins including ventricular myosin regulatory light chain (RLC). FHC often leads to malignant outcomes and sudden cardiac death. The FHC mutations ar...

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Detalhes bibliográficos
Main Authors: Mettikolla, P., Calander, N., Luchowski, R., Gryczynski, I., Gryczynski, Z., Zhao, J., Szczesna-Cordary, D., Borejdo, J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152379/
https://ncbi.nlm.nih.gov/pubmed/21723297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2011.06.014
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