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Familial Hypertrophic Cardiomyopathy can be Characterized by a Specific Pattern of Orientation Fluctuations of Actin Molecules

A single-point mutation in the gene encoding the ventricular myosin regulatory light chain (RLC) is sufficient to cause familial hypertrophic cardiomyopathy (FHC). Most likely, the underlying cause of this disease is an inefficient energy utilization by the mutated cardiac muscle. We set out to devi...

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Autori principali: Borejdo, J., Szczesna-Cordary, D., Muthu, P., Calander, N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892420/
https://ncbi.nlm.nih.gov/pubmed/20509708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1006749
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