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Diversity and Similarity of Motor Function and Cross-Bridge Kinetics in Papillary Muscles of Transgenic Mice Carrying Myosin Regulatory Light Chain Mutations D166V and R58Q

Mechanical properties of skinned papillary muscle fibers from transgenic mice expressing familial hypertrophic cardiomyopathy associated mutations D166V and R58Q in myosin regulatory light chain were investigated. Elementary steps and the apparent rate constants of the cross-bridge cycle were charac...

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Detalhes bibliográficos
Main Authors: Wang, Li, Muthu, Priya, Szczesna-Cordary, Danuta, Kawai, Masataka
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3809071/
https://ncbi.nlm.nih.gov/pubmed/23727233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2013.05.012
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