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Effects of DNA and protein size on substrate cleavage by human tyrosyl-DNA phosphodiesterase 1 (TDP1)
Tyrosyl-DNA phosphodiesterase 1 (TDP1) catalyzes the hydrolysis of phosphodiester linkages between a DNA 3′ phosphate and a tyrosine residue as well as a variety of other DNA 3′ substituents, and has been implicated in the repair of covalent complexes involving eukaryotic type IB topoisomerases. To...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3151729/ https://ncbi.nlm.nih.gov/pubmed/21463258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20101841 |
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