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Nonsense-mediated mRNA decay (NMD) in animal embryogenesis: to die or not to die, that is the question
Nonsense-mediated mRNA decay (NMD) is a well-studied cellular quality-control pathway. It decreases the half-lives of eukaryotic mRNAs that aberrantly contain premature termination codons and additionally regulates an estimated 10–20% of normal transcripts. NMD factors play crucial roles during embr...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3150509/ https://ncbi.nlm.nih.gov/pubmed/21550797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2011.03.008 |
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