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Nonsense-mediated mRNA decay (NMD) in animal embryogenesis: to die or not to die, that is the question

Nonsense-mediated mRNA decay (NMD) is a well-studied cellular quality-control pathway. It decreases the half-lives of eukaryotic mRNAs that aberrantly contain premature termination codons and additionally regulates an estimated 10–20% of normal transcripts. NMD factors play crucial roles during embr...

詳細記述

保存先:
書誌詳細
主要な著者: Hwang, Jungwook, Maquat, Lynne E.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150509/
https://ncbi.nlm.nih.gov/pubmed/21550797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2011.03.008
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