Glycoengineered Pichia produced anti-HER2 is comparable to trastuzumab in preclinical study

Mammalian cell culture systems are used predominantly for the production of therapeutic monoclonal antibody (mAb) products. A number of alternative platforms, such as Pichia engineered with a humanized N-linked glycosylation pathway, have recently been developed for the production of mAbs. The glyco...

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Detalhes bibliográficos
Main Authors: Zhang, Ningyan, Liu, Liming, Dumitru, Calin Dan, Cummings, Nga Rewa Houston, Cukan, Michael, Jiang, Youwei, Li, Yuan, Li, Fang, Mitchell, Teresa, Mallem, Muralidhar R, Ou, Yangsi, Patel, Rohan N, Vo, Kim, Wang, Hui, Burnina, Irina, Choi, Byung-Kwon, Huber, Hans, Stadheim, Terrance A, Zha, Dongxing
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149709/
https://ncbi.nlm.nih.gov/pubmed/21487242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.3.3.15532
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