Recombinant human lactoferrin expressed in glycoengineered Pichia pastoris: effect of terminal N-acetylneuraminic acid on in vitro secondary humoral immune response

Traditional production of therapeutic glycoproteins relies on mammalian cell culture technology. Glycoproteins produced by mammalian cells invariably display N-glycan heterogeneity resulting in a mixture of glycoforms the composition of which varies from production batch to production batch. However...

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Autors principals: Choi, Byung-Kwon, Actor, Jeffrey K., Rios, Sandra, d'Anjou, Marc, Stadheim, Terrance A., Warburton, Shannon, Giaccone, Erin, Cukan, Michael, Li, Huijuan, Kull, Angela, Sharkey, Nathan, Gollnick, Paul, Kocięba, Maja, Artym, Jolanta, Zimecki, Michal, Kruzel, Marian L., Wildt, Stefan
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2551750/
https://ncbi.nlm.nih.gov/pubmed/18365311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10719-008-9123-y
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