Electronic Structure of Neighboring Extein Residue Modulates Intein C-Terminal Cleavage Activity

Protein splicing is an autocatalytic reaction where an intervening element (intein) is excised and the remaining two flanking sequences (exteins) are joined. The reaction requires specific conserved residues, and activity may be affected by both the intein and the extein sequence. Predicting how seq...

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Bibliographische Detailangaben
Hauptverfasser: Shemella, Philip T., Topilina, Natalya I., Soga, Ikko, Pereira, Brian, Belfort, Georges, Belfort, Marlene, Nayak, Saroj K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2011
Schlagworte:
Protein
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149237/
https://ncbi.nlm.nih.gov/pubmed/21539790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.02.037
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