Electronic Structure of Neighboring Extein Residue Modulates Intein C-Terminal Cleavage Activity

Protein splicing is an autocatalytic reaction where an intervening element (intein) is excised and the remaining two flanking sequences (exteins) are joined. The reaction requires specific conserved residues, and activity may be affected by both the intein and the extein sequence. Predicting how seq...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Shemella, Philip T., Topilina, Natalya I., Soga, Ikko, Pereira, Brian, Belfort, Georges, Belfort, Marlene, Nayak, Saroj K.
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2011
Sujets:
Protein
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149237/
https://ncbi.nlm.nih.gov/pubmed/21539790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.02.037
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