Electronic Structure of Neighboring Extein Residue Modulates Intein C-Terminal Cleavage Activity

Protein splicing is an autocatalytic reaction where an intervening element (intein) is excised and the remaining two flanking sequences (exteins) are joined. The reaction requires specific conserved residues, and activity may be affected by both the intein and the extein sequence. Predicting how seq...

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Bibliografische gegevens
Hoofdauteurs: Shemella, Philip T., Topilina, Natalya I., Soga, Ikko, Pereira, Brian, Belfort, Georges, Belfort, Marlene, Nayak, Saroj K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Biophysical Society 2011
Onderwerpen:
Protein
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149237/
https://ncbi.nlm.nih.gov/pubmed/21539790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.02.037
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