TGF-β/Smad3 Signaling Promotes Renal Fibrosis by Inhibiting miR-29

TGF-β/Smad3 signaling promotes fibrosis, but the development of therapeutic interventions involving this pathway will require the identification and ultimate targeting of downstream fibrosis-specific genes. In this study, using a microRNA microarray and real-time PCR, wild-type mice had reduced expr...

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Autori principali: Qin, Wei, Chung, Arthur C.K., Huang, Xiao R., Meng, Xiao-Ming, Hui, David S.C., Yu, Cheuk-Man, Sung, Joseph J.Y., Lan, Hui Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2011
Soggetti:
Basic Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148701/
https://ncbi.nlm.nih.gov/pubmed/21784902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010121308
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