miR-29b as a Therapeutic Agent for Angiotensin II-induced Cardiac Fibrosis by Targeting TGF-β/Smad3 signaling

Loss of miR-29 is associated with cardiac fibrosis. This study examined the role and therapeutic potential of miR-29 in mouse model of hypertension induced by angiotensin II (AngII). By using microRNA microarray, in situ hybridization, and real-time polymerase chain reaction, we found that AngII-ind...

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Detalhes bibliográficos
Main Authors: Zhang, Yang, Huang, Xiao-Ru, Wei, Li-Hua, Chung, Arthur CK, Yu, Cheuk-Man, Lan, Hui-Yao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015231/
https://ncbi.nlm.nih.gov/pubmed/24569834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.25
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