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A Partially Folded Structure of Amyloid-Beta(1-40) in an Aqueous Environment

Aggregation of the Aβ(1-40) peptide is linked to the development of extracellular plaques characteristic of Alzheimer’s disease. While previous studies commonly show the Aβ(1-40) is largely unstructured in solution, we show that Aβ(1-40) can adopt a compact, partially folded structure. In this struc...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Vivekanandan, Subramanian, Brender, Jeffrey R., Lee, Shirley Y., Ramamoorthy, Ayyalusamy
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148408/
https://ncbi.nlm.nih.gov/pubmed/21726530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.06.133
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