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A Partially Folded Structure of Amyloid-Beta(1-40) in an Aqueous Environment
Aggregation of the Aβ(1-40) peptide is linked to the development of extracellular plaques characteristic of Alzheimer’s disease. While previous studies commonly show the Aβ(1-40) is largely unstructured in solution, we show that Aβ(1-40) can adopt a compact, partially folded structure. In this struc...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3148408/ https://ncbi.nlm.nih.gov/pubmed/21726530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.06.133 |
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