Function of the asparagine 74 residue of the inhibitory γ-subunit of retinal rod cGMP-phophodiesterase (PDE) in vivo

The inhibitory subunit of rod cyclic guanosine monophosphate (cGMP) phosphodiesterase, PDE6γ, is a major component of rod transduction and is required to support photoreceptor integrity. The N74A allele of PDE6γ has previously been shown in experiments carried out in vitro to reduce the regulatory i...

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Hauptverfasser: Tsang, Stephen H., Woodruff, Michael L., Hsu, Chun Wei, Naumann, Matthew C., Cilluffo, Marianne, Tosi, Joaquin, Lin, Chyuan-Sheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148328/
https://ncbi.nlm.nih.gov/pubmed/21616145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.05.007
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