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Light-dependent phosphorylation of the gamma subunit of cGMP-Phophodiesterase (PDE6γ) at residue threonine 22 in intact photoreceptor neurons

The γ subunit of rod-specific cGMP phosphodiesterase 6 (PDE6γ), an effector of the G-protein GNAT1, is a key regulator of phototransduction. The results of several in vitro biochemical reconstitution experiments conducted to examine the effects of phosphorylation of PDE6γ on its ability to regulate...

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Detalhes bibliográficos
Main Authors: Janisch, Kerstin M, Kasanuki, J. Mie, Naumann, Matthew C, Davis, Richard J, Lin, Chyuan-Sheng, Semple-Rowland, Susan, Tsang, Stephen H
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787723/
https://ncbi.nlm.nih.gov/pubmed/19878658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.10.106
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