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Function of the asparagine 74 residue of the inhibitory γ-subunit of retinal rod cGMP-phophodiesterase (PDE) in vivo

The inhibitory subunit of rod cyclic guanosine monophosphate (cGMP) phosphodiesterase, PDE6γ, is a major component of rod transduction and is required to support photoreceptor integrity. The N74A allele of PDE6γ has previously been shown in experiments carried out in vitro to reduce the regulatory i...

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Detalhes bibliográficos
Main Authors: Tsang, Stephen H., Woodruff, Michael L., Hsu, Chun Wei, Naumann, Matthew C., Cilluffo, Marianne, Tosi, Joaquin, Lin, Chyuan-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148328/
https://ncbi.nlm.nih.gov/pubmed/21616145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.05.007
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