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Function of the asparagine 74 residue of the inhibitory γ-subunit of retinal rod cGMP-phophodiesterase (PDE) in vivo

The inhibitory subunit of rod cyclic guanosine monophosphate (cGMP) phosphodiesterase, PDE6γ, is a major component of rod transduction and is required to support photoreceptor integrity. The N74A allele of PDE6γ has previously been shown in experiments carried out in vitro to reduce the regulatory i...

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Hlavní autoři: Tsang, Stephen H., Woodruff, Michael L., Hsu, Chun Wei, Naumann, Matthew C., Cilluffo, Marianne, Tosi, Joaquin, Lin, Chyuan-Sheng
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148328/
https://ncbi.nlm.nih.gov/pubmed/21616145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.05.007
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