Pomalidomide augments fetal hemoglobin production without the myelosuppressive effects of hydroxyurea in transgenic sickle cell mice

Pharmacologic induction of fetal hemoglobin (HbF) expression is an effective treatment strategy for sickle cell disease (SCD) and β-thalassemia. Pomalidomide is a potent structural analog of thalidomide and member of a new class of immunomodulatory drugs. Recent reports demonstrated that pomalidomid...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Meiler, Steffen E., Wade, Marlene, Kutlar, Ferdane, Yerigenahally, Shobha D., Xue, Yongjun, Moutouh-de Parseval, Laure A., Corral, Laura G., Swerdlow, Paul S., Kutlar, Abdullah
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Red Cells, Iron, and Erythropoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148160/
https://ncbi.nlm.nih.gov/pubmed/21536862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-11-319137
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados