ロード中...

Multiple CCR5 Conformations on the Cell Surface Are Used Differentially by Human Immunodeficiency Viruses Resistant or Sensitive to CCR5 Inhibitors

Resistance to small-molecule CCR5 inhibitors arises when HIV-1 variants acquire the ability to use inhibitor-bound CCR5 while still recognizing free CCR5. Two isolates, CC101.19 and D1/85.16, became resistant via four substitutions in the gp120 V3 region and three in the gp41 fusion peptide (FP), re...

詳細記述

保存先:
書誌詳細
主要な著者: Berro, Reem, Klasse, Per Johan, Lascano, Danny, Flegler, Ayanna, Nagashima, Kirsten A., Sanders, Rogier W., Sakmar, Thomas P., Hope, Thomas J., Moore, John P.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147974/
https://ncbi.nlm.nih.gov/pubmed/21680525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00767-11
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!