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CCR5 Conformations Are Dynamic and Modulated by Localization, Trafficking and G Protein Association
CCR5 acts as the principal coreceptor during HIV-1 transmission and early stages of infection. Efficient HIV-1 entry requires a series of processes, many dependent on the conformational state of both viral envelope protein and cellular receptor. Monoclonal antibodies (MAbs) are able to identify diff...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3938464/ https://ncbi.nlm.nih.gov/pubmed/24586501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089056 |
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