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CCR5 conformations are dynamic and modulated by localization, trafficking and G protein association.
CCR5 acts as the principal coreceptor during HIV-1 transmission and early stages of infection. Efficient HIV-1 entry requires a series of processes, many dependent on the conformational state of both viral envelope protein and cellular receptor. Monoclonal antibodies (MAbs) are able to identify diff...
Guardat en:
| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science (PLoS)
2014-01-01
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| Col·lecció: | PLoS ONE |
| Accés en línia: | http://europepmc.org/articles/PMC3938464?pdf=render |
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