Nuclear Receptors TR2 and TR4 Recruit Multiple Epigenetic Transcriptional Corepressors That Associate Specifically with the Embryonic β-Type Globin Promoters in Differentiated Adult Erythroid Cells

Nuclear receptors TR2 and TR4 (TR2/TR4) were previously shown to bind in vitro to direct repeat elements in the mouse and human embryonic and fetal β-type globin gene promoters and to play critical roles in the silencing of these genes. By chromatin immunoprecipitation (ChIP) we show that, in adult...

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Main Authors: Cui, Shuaiying, Kolodziej, Katarzyna E., Obara, Naoshi, Amaral-Psarris, Alexandra, Demmers, Jeroen, Shi, Lihong, Engel, James Douglas, Grosveld, Frank, Strouboulis, John, Tanabe, Osamu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147791/
https://ncbi.nlm.nih.gov/pubmed/21670149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05310-11
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