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The orphan nuclear receptor TR4 regulates erythroid cell proliferation and maturation

The orphan nuclear receptors TR4 (NR2C2) and TR2 (NR2C1) are the DNA-binding subunits of the macromolecular complex, direct repeat erythroid-definitive, which has been shown to repress ε- and γ-globin transcription during adult definitive erythropoiesis. Previous studies implied that TR2 and TR4 act...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Lee, Mary P., Tanabe, Osamu, Shi, Lihong, Jearawiriyapaisarn, Natee, Lucas, Daniel, Engel, James Douglas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5721283/
https://ncbi.nlm.nih.gov/pubmed/29018082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-05-783159
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