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The TR2 and TR4 orphan nuclear receptors repress Gata1 transcription

When the orphan nuclear receptors TR2 and TR4, the DNA-binding subunits of the DRED repressor complex, are forcibly expressed in erythroid cells of transgenic mice, embryos exhibit a transient mid-gestational anemia as a consequence of a reduction in the number of primitive erythroid cells. GATA-1 m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tanabe, Osamu, Shen, Yannan, Liu, Qinghui, Campbell, Andrew D., Kuroha, Takashi, Yamamoto, Masayuki, Engel, James Douglas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045135/
https://ncbi.nlm.nih.gov/pubmed/17974920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1593307
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