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An embryonic/fetal β-type globin gene repressor contains a nuclear receptor TR2/TR4 heterodimer
We recently described an erythroid ε-globin gene repressor activity, which we named DRED (direct repeat erythroid-definitive). We show that DRED binds with high affinity to DR1 sites in the human embryonic (ε-) and fetal (γ-) globin gene promoters, but the adult β-globin promoter has no DR1 element....
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2002
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC126089/ https://ncbi.nlm.nih.gov/pubmed/12093744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf340 |
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