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Compound loss of function of nuclear receptors Tr2 and Tr4 leads to induction of murine embryonic β-type globin genes

The orphan nuclear receptors TR2 and TR4 have been shown to play key roles in repressing the embryonic and fetal globin genes in erythroid cells. However, combined germline inactivation of Tr2 and Tr4 leads to periimplantation lethal demise in inbred mice. Hence, we have previously been unable to ex...

詳細記述

保存先:
書誌詳細
出版年:Blood
主要な著者: Cui, Shuaiying, Tanabe, Osamu, Sierant, Michael, Shi, Lihong, Campbell, Andrew, Lim, Kim-Chew, Engel, James Douglas
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342359/
https://ncbi.nlm.nih.gov/pubmed/25561507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-10-605022
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