An embryonic/fetal β-type globin gene repressor contains a nuclear receptor TR2/TR4 heterodimer

We recently described an erythroid ε-globin gene repressor activity, which we named DRED (direct repeat erythroid-definitive). We show that DRED binds with high affinity to DR1 sites in the human embryonic (ε-) and fetal (γ-) globin gene promoters, but the adult β-globin promoter has no DR1 element....

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Bibliographic Details
Main Authors: Tanabe, Osamu, Katsuoka, Fumiki, Campbell, Andrew D., Song, Weimin, Yamamoto, Masayuki, Tanimoto, Keiji, Engel, James Douglas
Format: Artigo
Language:Inglês
Published: Oxford University Press 2002
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC126089/
https://ncbi.nlm.nih.gov/pubmed/12093744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf340
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