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Immunological Origin and Functional Properties of Catalytic Autoantibodies to Amyloid β Peptide

OBJECTIVES: Objectives The objectives of this study are to (1) evaluate the ability of the immune system to synthesize specific antibodies that catalyze the degradation of amyloid β peptide (Aβ) and to (2) evaluate the prospect of developing a catalytic IVIG (CIVIG) formulation for therapy of Alzhei...

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Detalhes bibliográficos
Main Authors: Paul, Sudhir, Planque, Stephanie, Nishiyama, Yasuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147076/
https://ncbi.nlm.nih.gov/pubmed/20454852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10875-010-9414-5
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