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Calpain-Mediated Tau Cleavage: A Mechanism Leading to Neurodegeneration Shared by Multiple Tauopathies
Tau dysfunction has been associated with a host of neurodegenerative diseases called tauopathies. These diseases share, as a common pathological hallmark, the presence of intracellular aggregates of hyperphosphorylated tau in affected brain areas. Aside from tau hyperphosphorylation, little is known...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
ScholarOne
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3146621/ https://ncbi.nlm.nih.gov/pubmed/21442128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2010.00220 |
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