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Calpain-Mediated Signaling Mechanisms in Neuronal Injury and Neurodegeneration
Calpain is a ubiquitous calcium-sensitive protease that is essential for normal physiologic neuronal function. However, alterations in calcium homeostasis lead to persistent, pathologic activation of calpain in a number of neurodegenerative diseases. Pathologic activation of calpain results in the c...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2726710/ https://ncbi.nlm.nih.gov/pubmed/18686046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-008-8036-x |
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