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Distinct Roles for μ-Calpain and m-Calpain in Synaptic NMDAR-Mediated Neuroprotection and Extrasynaptic NMDAR-Mediated Neurodegeneration

Prolonged calpain activation is widely recognized as a key component of neurodegeneration in a variety of pathological conditions. Numerous reports have also indicated that synaptic activation of NMDA receptors (NMDARs) provides neuroprotection against a variety of insults. Here, we report the parad...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Yubin, Briz, Victor, Chishti, Athar, Bi, Xiaoning, Baudry, Michel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3841454/
https://ncbi.nlm.nih.gov/pubmed/24285894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3293-13.2013
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