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Calpain-1 and calpain-2: the yin and yang of synaptic plasticity and neurodegeneration

Many signaling pathways participate in both synaptic plasticity and neuronal degeneration. While calpains participate in these phenomena, very few studies have evaluated the respective roles of the two major calpain isoforms in the brain, calpain-1 and calpain-2. We review recent studies indicating...

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Detalhes bibliográficos
Publicado no:Trends Neurosci
Main Authors: Baudry, Michel, Bi, Xiaoning
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818674/
https://ncbi.nlm.nih.gov/pubmed/26874794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2016.01.007
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