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Inhibition of morphine-induced cAMP overshoot: a cell-based assay model in a high-throughput format

Opiates are potent analgesics but also drugs of abuse mainly because they produce euphoria. Chronic use of opiates results in the development of tolerance and dependence. Dr Marshall Nirenberg’s group at the National Institutes of Health (NIH) was the first to use a cellular model system of Neurobla...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Xia, Menghang, Guo, Vicky, Huang, Ruili, Shahane, Sampada A., Austin, Christopher P., Nirenberg, Marshall, Sharma, Shail K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146558/
https://ncbi.nlm.nih.gov/pubmed/21598037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10571-011-9689-y
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