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Inhibition of morphine-induced cAMP overshoot: a cell-based assay model in a high-throughput format

Opiates are potent analgesics but also drugs of abuse mainly because they produce euphoria. Chronic use of opiates results in the development of tolerance and dependence. Dr Marshall Nirenberg’s group at the National Institutes of Health (NIH) was the first to use a cellular model system of Neurobla...

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Detalhes bibliográficos
Main Authors: Xia, Menghang, Guo, Vicky, Huang, Ruili, Shahane, Sampada A., Austin, Christopher P., Nirenberg, Marshall, Sharma, Shail K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146558/
https://ncbi.nlm.nih.gov/pubmed/21598037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10571-011-9689-y
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