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A new homogeneous high-throughput screening assay for profiling compound activity on the human ether-a-go-go-related gene channel

Long QT syndrome, either inherited or acquired from drug treatments, can result in ventricular arrhythmia (torsade de pointes) and sudden death. Human ether-a-go-go-related gene (hERG) channel inhibition by drugs is now recognized as a common reason for the acquired form of long QT syndrome. It has...

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Detalhes bibliográficos
Main Authors: Titus, Steven A., Beacham, Daniel, Shahane, Sampada A., Southall, Noel, Xia, Menghang, Huang, Ruili, Hooten, Elizabeth, Zhao, Yong, Shou, Louie, Austin, Christopher P., Zheng, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766802/
https://ncbi.nlm.nih.gov/pubmed/19583963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2009.07.003
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