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Detection of Phospholipidosis Induction: A Cell-Based Assay in High-Throughput and High–Content Format

Drug-induced phospholipidosis is characterized by the accumulation of intracellular phospholipids in cells exposed to cationic amphiphilic drugs. The appearance of unicentric or multicentric multi-lamellar bodies viewed under electron microscope (EM) is the morphological hallmark of phospholipidosis...

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Detalhes bibliográficos
Publicado no:J Biomol Screen
Main Authors: Shahane, Sampada A., Huang, Ruili, Gerhold, David, Baxa, Ulrich, Austin, Christopher P., Xia, Menghang
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550094/
https://ncbi.nlm.nih.gov/pubmed/24003057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057113502851
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